The following sections will assume Cyno is being played on a Stellar-Conduct team, where his gameplay loop can be summarized as follows,
Setup buffs and consistent Cryo application for Cyno alongside a teammate that enables Stellar-Conduct.
Basic Combos
C0: QE N5 N4E 2[N5 N2E]
Optimized Combos
C0: QE N4d N4E 2[N4d N4E]C1+: QE 2[N4d] N2E 2[N4d N4E]
For C6, you want to end the combo with another N1 to get off an extra Duststalker Bolt for a little extra damage without much rotation extension. Extending the rotation to get 4 Endseers is also a viable choice for a highly-invested C6 Cyno.
N Normal AttackC Charged AttackE Elemental SkillQ Elemental Burst